Palladium-Catalyzed Homocoupling Reaction of 1-Iodoalkynes: A Simple and Efficient Synthesis of Symmetrical 1,3-Diynes

Abstract

This paper describes a highly efficient synthetic method of symmetrical 1,3-diynes from 1-iodoalkynes in the presence of 4 mol % Pd(PPh(3))(4) in DMF at room temperature under a nitrogen atmosphere without any use of additives and other metals.