Concepedia

Long-Term Renal Function in Liver Transplant Recipients After Conversion From Calcineurin Inhibitors to mTOR Inhibitors

Anna Hüsing, Martina Schmidt, Susanne Beckebaum, Vito R. Cicinnati, Raphael Koch, Gerold Thölking, Jaqueline Stella, Hauke Heinzow, Hartmut Schmidt, Iyad Kabar

Annals of Transplantation · 2015 · 13 citations · 10 references

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Abstract

Conversion from CNI-based to CNI-free, mTOR inhibitor-based immunosuppression after LT is safe and can result in significant renal recovery. CNI-free, mTOR inhibitor-based immunosuppression is a potential option for patients with contraindications for CNIs and for LT recipients with rapid reduction in kidney function due to CNIs.

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A Randomized, Controlled Study to Assess the Conversion From Calcineurin-Inhibitors to Everolimus After Liver Transplantation—PROTECT

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