Phase II study of medroxyprogesterone acetate plus metformin as a fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer

Metformin and reduced risk of cancer in diabetic patients

Josie Evans, Louise A. Donnelly, Alistair Emslie‐Smith et al. · BMJ · 2005 · 2.4K citations · Full text

Public Health, Health Sciences, Infectious Diseases +14

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

Marc Foretz, Sophie Hébrard, Jocelyne Leclerc et al. · Journal of Clinical Investigation · 2010 · 1.2K citations · Full text

Life Sciences, Biochemistry, Physiology +17

Multicenter Phase II Study of Fertility-Sparing Treatment With Medroxyprogesterone Acetate for Endometrial Carcinoma and Atypical Hyperplasia in Young Women

Kimio Ushijima, Hideaki Yahata, Hiroyuki Yoshikawa et al. · Journal of Clinical Oncology · 2007 · 413 citations · Full text

Medicine, Oncology, Pharmacotherapy +9

Conservative therapy for adenocarcinoma and atypical endometrial hyperplasia of the endometrium in young women: central pathologic review and treatment outcome

Tsunehisa Kaku, Hiroyuki Yoshikawa, Hitoshi Tsuda et al. · Cancer Letters · 2001 · 245 citations

Medicine, Gynecology, Oncology +13

Metformin is associated with improved survival in endometrial cancer

Emily Ko, Paige Walter, Amanda Jackson et al. · Gynecologic Oncology · 2013 · 159 citations

Medicine, Oncology, Pharmacology +5