Relative <i>ortho</i>‐directing power of fluorine, chlorine and methoxy group for the metalation reaction in the diazine series. Diazines XXXV

Abstract

Abstract The regioselectivity of the metalation of 2‐chloro‐6‐methoxypyrazine, 2‐fluoro‐6‐methoxypyrazine and 3‐fluoro‐6‐chloropyridazine was studied; the relative ortho ‐directing power was F &gt; OMe &gt; Cl.