Journal of Bacteriology · 2002 · 80 citations · 13 references
Life SciencesGeneticsMicrobiologyComparative GenomicsHost-pathogen InteractionsMicrobial PathogenesisBacterial PathogenesisBacterial Virulence FactorsMicrobial Virulence FactorsPathogen GenomicsPathogen Virulence FactorsVirulence Gene RegulationBacterial Virulence GenesCellular ChemotaxisChemotaxisVirulence Factor ExpressionVirulence Gene Expression
The Vibrio cholerae genome revealed the presence of multiple sets of chemotaxis genes, including three cheA gene homologs. We found that the cheA-2, but not cheA-1 or cheA-3, gene is essential for chemotaxis under standard conditions. Loss of chemotaxis had no effect on virulence factor expression in vitro.
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