<i>ALK</i> Rearrangements Are Mutually Exclusive with Mutations in <i>EGFR</i> or <i>KRAS</i>: An Analysis of 1,683 Patients with Non–Small Cell Lung Cancer - Concepedia

Concepedia

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<i>ALK</i> Rearrangements Are Mutually Exclusive with Mutations in <i>EGFR</i> or <i>KRAS</i>: An Analysis of 1,683 Patients with Non–Small Cell Lung Cancer

DOI Full Paper Access

582

Citations

40

References

2013

Year

Justin F. Gainor, Anna M. Varghese, Sai‐Hong Ignatius Ou, Sheheryar Kabraji, Mark M. Awad, Ryohei Katayama, Amanda C. Pawlak, Mari Mino–Kenudson, Beow Y. Yeap, Gregory J. Riely,

Clinical Cancer Research

Abstract

Functional ALK rearrangements were mutually exclusive with EGFR and KRAS mutations in a large Western patient population. This lack of overlap was also observed in ALK-positive cancers with acquired resistance to crizotinib.

References

	Year	Citations

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