Thorax · 1984 · 23 citations · 3 references
PharmacyPharmacologyPharmacotherapyPulmonary Function TestingPulmonologyRespiratory PharmacotherapyBronchodilator TherapyInhalation Dosage FormsInhalation TherapyPeak Expiratory FlowRespiratory DiseaseRespiratory MedicineAirflow Obstruction ReliefBronchodilator Dose-responseBronchodilator DosingBronchodilator EfficacyChronic Bronchitis TreatmentClinically Significant Bronchodilator ResponseForced Vital Capacity ChangeInhaled Bronchodilator Administration
In a dose response study 12 patients with chronic bronchitis and airflow obstruction received inhaled placebo and incremental doses of oxitropium bromide. Significant improvements in peak expiratory flow rate, forced expiratory volume in one second, and forced vital capacity were recorded at all times up to 10 hours after all doses of oxitropium bromide. Oxitropium bromide is an effective bronchodilator in chronic bronchitis with an optimal dose of 400-600 micrograms.
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Multiple Range and Multiple F Tests
David B. Duncan · Biometrics · 1955 · 23.2K citations
Peak Expiratory Flow in Normal Subjects
Ian Gregg, Andrew Nunn · BMJ · 1973 · 204 citations · Full text