<i>Speleands</i>. Macropolycyclic receptor cages based on binding and shaping sub‐units. Synthesis and properties of macrocycle cyclotriveratrylene combinations. Preliminary communication

Abstract

Abstract Combination of a receptor unit with a rigid shaping unit produces a new type of receptor molecules of the cryptand class, hollow macropolycyclic molecules termed speleands , capable of substrate inclusion. Two members of this category of compounds 1 and 2 , have been synthesized by connecting in a single step, a macro‐cyclic [18]‐N 3 O 3 binding unit with a rigid cyclotriveratrylene unit via three bridges. Compound 1 binds the rnethylammonium cation forming both external and internal complexes; for the latter a ‘ speleme ’ structure, schematically represented by 15 , may be proposed.