Multidisciplinary Respiratory Medicine · 2012 · 25 citations · 18 references
MedicineEmergency MedicineInternal MedicineHospital MedicinePulmonary Function TestingPulmonologyChronic Obstructive Pulmonary DiseaseRespiratory DiseaseRespiratory MedicineAntibiotic Therapy For ExacerbationsChronic Obstructive Pulmonary Disease EpidemiologyExacerbation Risk StratificationObservational Study AnalysisOxygenationPulmonary Exacerbations
BACKGROUND: The aim of this study was to determine the frequency of COPD exacerbations in our Emergency Department, as well as the hospitalization-related factors. METHODS: Prospective observational study conducted in the Emergency Department of Salnés County Hospital among patients admitted for COPD exacerbation. Admission predictors were determined by multivariate analysis. RESULTS: There were 409 exacerbations in 239 patients (79% male, mean age 75). 57% of exacerbations required hospitalization. Hospitalization-related factors were impaired oxygenation (p < 0.001), presence of neutrophilia (p < 0.01) and prescription of antibiotics in the Emergency Department (p < 0.05). CONCLUSIONS: COPD exacerbation accounts for over 1% of all visits to our Emergency Department. 57% of them required hospitalization. Impaired oxygenation, greater neutrophilia and prescription of antibiotics in the Emergency Department were associated with greater probability of admission.
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Thomas R. Prentice · Res Medica · 2013 · 1.7K citations · Full text
Geographic Variations in Prevalence and Underdiagnosis of COPD
Victor Sobradillo Penña, Marc Miravitlles, Rafael Gabriel et al. · CHEST Journal · 2000 · 664 citations