The first Au-nanoparticles catalyzed green synthesis of propargylamines via a three-component coupling reaction of aldehyde, alkyne and amine

Abstract

Recyclable Au-nanoparticles provide an efficient, economic, novel route for multi component A3 coupling reaction of aldehyde, amine and alkyne. This method provides the wide range of substrate applicability. This protocol avoids the use of heavy metals, co-catalyst and gives the propargylamine in excellent yields.