Chemoselective Hydrogenation Catalyzed by Pd on Spherical Carbon

Abstract

Abstract We have developed a highly chemoselective hydrogenation method using a novel palladium catalyst supported on spherical carbon (0.5 % Pd/SC). The 0.5 % Pd/SC exhibited a novel catalytic activity and could achieve the chemoselective hydrogenation of alkynes, alkenes, azides, nitro groups, and aliphatic O ‐ tert ‐butyldimethylsilyl (TBS) ethers without hydrogenolysis of benzyl esters, benzyl ethers, nitriles, aromatic ketones, N ‐carbobenzyloxy ( N ‐Cbz) protective groups, and aromatic O ‐TBS ethers.