Concepedia

Abnormal nitric oxide metabolism in systemic sclerosis: increased levels of nitrated proteins and asymmetric dimethylarginine

Audrey Dooley, Beirong Gao, N. J. Bradley, David Abraham, C. M. Black, M. Jacobs, K. R. Bruckdorfer

Lara D. Veeken · 2006 · 103 citations · 40 references

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Abstract

NO formation is increased in patients with primary RP or lSSc, but nitration of proteins and elevated ADMA is a particular feature of dSSc and may reflect abnormal NO regulation and/or contribute to endothelial dysfunction in SSc.

References

40

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 54.9K citations

, , +11

Preliminary criteria for the classification of systemic sclerosis (scleroderma)

Alfonse T. Masi · Arthritis & Rheumatism · 1980 · 4.9K citations

Evidence for <i>In Vivo</i> Peroxynitrite Production in Human Acute Lung Injury

Neil W. Kooy, James A. Royall, Yao Z. Ye et al. · American Journal of Respiratory and Critical Care Medicine · 1995 · 484 citations

, , +18

Sequential dermal microvascular and perivascular changes in the development of scleroderma

R. J. Prescott, Anthony J. Freemont, Carolyn Jones et al. · The Journal of Pathology · 1992 · 384 citations

Peroxynitrite disables the tyrosine phosphorylation regulatory mechanism: Lymphocyte-specific tyrosine kinase fails to phosphorylate nitrated cdc2(6-20)NH2 peptide.

S. K. Kong, Moon B. Yim, Earl R. Stadtman et al. · Proceedings of the National Academy of Sciences · 1996 · 338 citations · Full text

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