Isolation and Identification of ATP-Secreting Bacteria from Mice and Humans

Abstract

ABSTRACT In a recent report, ATP, which was possibly secreted by some intestinal bacteria, was shown to cause colitis in mice via Th17 cell differentiation. However, the ATP-secreting bacteria have not been isolated and identified. In the present study, we report that Enterococcus gallinarum , which is a vancomycin-resistant Gram-positive coccus isolated from mice and humans, secretes ATP.