Xpert MTB/RIF for Rapid Diagnosis of Tuberculous Lymphadenitis from Fine-Needle-Aspiration Biopsy Specimens

Louis J. Ligthelm, Mark P. Nicol, Kim G.P. Hoek, Rachael K. Jacobson, Paul D. van Helden, Ben J. Marais, Robin M. Warren, Colleen A. Wright

Journal of Clinical Microbiology · 2011 · 121 citations · 14 references

DOIFull text

Open access

Concepts

Abstract

This study demonstrates the excellent diagnostic accuracy of the Xpert MTB/RIF test in patients with tuberculous lymphadenitis. The test sensitivity and specificity were 96.7% (95% confidence interval [CI], 86.6 to 100%) and 88.9% (95% CI, 69.6 to 100%), respectively, and it correctly identified 6/6 (100%) of the cytology smear-negative/culture-positive cases and 1 of 2 (50%) rifampin-resistant cases.

References

14