Spectrally Resolved Magnetic Resonance Imaging of a Xenon Biosensor

Abstract

Going hyper: A continuous flow of water saturated with hyperpolarized xenon through a glass tube assembly containing a xenon biosensor attached through its biotin tag to immobilized avidin–agarose beads (see picture) packed in between two frits results in distinct NMR signals that allow detection of the immobilized avidin analyte with high sensitivity.