Further Observations on the Pathology of Pulmonary Emphysema in Chronic Bronchitics

Abstract

In a previous communication, methods for demonstrating the pathology of pulmonary emphysema were described (Heard, 1958). Centrilobular and diffuse varieties were illustrated, each being localized or widespread. The present communication records the detailed appearances of normal lungs by these methods and compares them with the changes of diffuse emphysema. METHODS Full details of the methods for pressure-fixing lungs and impregnating slices with barium sulphate were given previously. Each lung was injected through the main bronchus with 20 % formalin at a pressure of 10 to 12 in. (25-30 cm.) and the pressure was