IS <i>Ecp1B</i> -Mediated Transposition of <i>bla</i> _CTX-M in <i>Escherichia coli</i>

Abstract

Several expanded-spectrum beta-lactamase bla(CTX-M) genes are associated with ISEcp1-like elements in Enterobacteriaceae. We found that ISEcp1B was able to mobilize the adjacent bla(CTX-M-19) gene by a transpositional mechanism in Escherichia coli by recognizing a variety of DNA sequences as right inverted repeats.