Cocrystals of gabapentin with C-alkylresorcin[4]arenes

Abstract

The synthesis of cocrystals of gabapentin (GBP) with resorcin[4]arenes (RsCn) with different tail lengths, C-hexylresorcin[4]arene (RsC6) and C-propylresorcin[4]arene (RsC3), is reported. The structural elucidations of the two cocrystals show differences in packing arrangements and host–guest interactions.