Advanced Synthesis & Catalysis · 2001 · 99 citations · 0 references
Natural SciencesChemistryCatalysisOrganic ChemistryOrganometallic ChemistryCoordination ChemistryHeterocyclic ChemistryLigand BindingLigand-based DesignCyclopropanation ReactionsEnantioselective CatalysisEnantioselective Catalyst DesignEnantioselective SynthesisEnantioselectivity
Cyclopropanation of styrene derivatives with alkyl α-diazoacetate in the presence of the second-generation (salen)cobalt(II) complex 6 proceeded with excellent cis- and enantioselectivity. On the other hand, the cyclopropanation in the presence of complex 14 which was designed on the basis of the mechanism of asymmetric induction by complex 6 showed good trans- and excellent enantioselectivity.