Association Studies of Catechol- <i>O</i> -Methyltransferase ( <i>COMT</i> ) Gene with Schizophrenia and Response to Antipsychotic Treatment

Abstract

The present study thus indicates that the interacting effects within the COMT gene polymorphisms may influence the disease status and response to risperidone in schizophrenia patients. However, the study needs to be replicated in a larger sample set for confirmation, followed by functional studies.