Life span and synapses: will there be a primary senile dementia?

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

Robert D. Terry, Eliezer Masliah, David P. Salmon et al. · Annals of Neurology · 1991 · 4.4K citations

Medicine, Neurology, Neuroscience +17

Dendritic Spine "Dysgenesis" and Mental Retardation

Dominick P. Purpura · Science · 1974 · 520 citations

Medicine, Genetics, Neuroscience +17

Quantitative synaptic alterations in the human neocortex during normal aging

Eliezer Masliah, Margaret Mallory, L A Hansen et al. · Neurology · 1993 · 412 citations

Medicine, Neurobiology, Neuroscience +17

Evidence for active synapse formation or altered postsynaptic metabolism in visual cortex of rats reared in complex environments.

William T. Greenough, Hwa-Min Hwang, Christopher B. Gorman · Proceedings of the National Academy of Sciences · 1985 · 197 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Low education is a genuine risk factor for accelerated memory decline and dementia

Ben Schmand, J. Lindeboom, Carolien Smits et al. · Journal of Clinical Epidemiology · 1997 · 119 citations

Medicine, Neurology, Psychology +16