Concepedia

Cancer testis antigens

Anil Suri, Shikha Saini, Abhilasha Sinha, Sumit Agarwal, Archana Verma, Deepak Parashar, Swarnendra Singh, Namita Gupta, Nirmala Jagadish

OncoImmunology · 2012 · 47 citations · 9 references

DOIFull text

Open access

Concepts

Abstract

Cancer immunotherapy is a promising field with limited success, also due to lack of tumor-specific targets. In our attempt of exploring novel biomarkers and immunotherapeutic targets against cancer, we have discovered a novel cancer testis antigen, SPAG9, in cancers of different histological origin and demonstrated its potential role in oncogenesis.

References

9

Cancer statistics, 2012

Rebecca L. Siegel, Deepa Naishadham, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2012 · 10.7K citations · Full text

, , +16

Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial

Ravi A. Madan, Mahsa Mohebtash, Philip M. Arlen et al. · The Lancet Oncology · 2012 · 327 citations · Full text

, , +17

Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients

Kunle Odunsi, Junko Matsuzaki, Julia Karbach et al. · Proceedings of the National Academy of Sciences · 2012 · 198 citations

, , +17

A Pilot Study of MUC-1/CEA/TRICOM Poxviral-Based Vaccine in Patients with Metastatic Breast and Ovarian Cancer

Mahsa Mohebtash, Kwong-Yok Tsang, Ravi A. Madan et al. · Clinical Cancer Research · 2011 · 129 citations · Full text

, , +17

Characterization of a novel human sperm-associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase-interacting protein

Nirmala Jagadish, Ritu Rana, R. Selvi et al. · Biochemical Journal · 2005 · 90 citations · Full text

, , +13