Berberine Attenuates Ischemia-Reperfusion Injury Via Regulation of Adenosine-5′-monophosphate Kinase Activity in Both Non-ischemic and Ischemic Areas of the Rat Heart

Structure of mammalian AMPK and its regulation by ADP

Bing Xiao, Matthew J. Sanders, E. Underwood et al. · Nature · 2011 · 917 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury

Raymond R. Russell, Ji Li, David Coven et al. · Journal of Clinical Investigation · 2004 · 723 citations · Full text

Life Sciences, Cardiology, Physiology +16

High Rates of Fatty Acid Oxidation during Reperfusion of Ischemic Hearts Are Associated with a Decrease in Malonyl-CoA Levels Due to an Increase in 5’-AMP-activated Protein Kinase Inhibition of Acetyl-CoA Carboxylase

Naomi Kudo, Amy Barr, Rick L. Barr et al. · Journal of Biological Chemistry · 1995 · 577 citations · Full text

Life Sciences, Biochemistry, Physiology +17

Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I

Nigel Turner, Jing-Ya Li, Alison K. Gosby et al. · Diabetes · 2008 · 520 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression

Hao Zhang, Jing Wei, Rong Xue et al. · Metabolism · 2009 · 433 citations

Medicine, Endocrinology, Pharmacology +13