Annual Review of Biochemistry · 1977 · 753 citations · 0 references
Life SciencesBiologyMolecular BiologyCell SignalingDevelopmental Cell BiologySignal TransductionDevelopmental ProliferationDevelopmental Signaling PathwaysGrowth PhysiologyMetabolic SignalingSignal Transduction PathwaysCell Fate Decision SignalingCell Growth RegulationCell Growth Signaling PathwaysHippo SignalingHippo Signaling PathwayOrgan Size ControlTissue GrowthTissue Growth Regulation
The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More