Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 1984 · 17 citations · 11 references
Veterinary MedicineImmunologyMolecular BiologyGenomicsParasite ImmunologyProtozoologyImmune Evasion By ParasitesMalariaParasite AntigensProtozoal InfectionsProtozoan Host-parasite InteractionsProtozoan ImmunologyImmune System ModulationMalaria GenomicsMalaria ImmunologyMalaria ParasitesParasite-associated AntigensProtozoan Surface AntigensSporozoite AntigensSporozoite Stage
The major surface antigen (circumsporozoite-protein) of the sporozoite stage of Plasmodium knowlesi has been cloned and characterized. The gene is notable for the presence of a 36 base pair unit repeated in tandem 12 times. These repeats may function at the DNA level in regulating gene expression and at the protein level in providing multiple copies of a single epitope (repitope) as part of a protein designed to evade and decoy the immune system.
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Transposition of R factor genes to bacteriophage lambda.
Douglas E. Berg, Julian Davies, Bernard Allet et al. · Proceedings of the National Academy of Sciences · 1975 · 390 citations · Full text
Structure of the plasmodium knowlesi gene coding for the circumsporozoite protein
Luiz S. Ozaki, Pamela Svec, Ruth S. Nussenzweig et al. · Cell · 1983 · 203 citations