Polymorphisms Within the Promoter Region of the Gamma Interferon (IFN-γ) Receptor1 Gene are Associated With the Susceptibility to Chronic HBV Infection in an Iranian Population

Abstract

Presence of G allele at position -611 within promoter of IFN-γ R1 gene in the enrolled population for the study was related to lower risk of disease, and presence of T allele at position -56 was also related to susceptibility to chronic HBV infection. Men had higher frequency of chronic HBV infection, which might be the result of high risk behavior.