Relationship Between Interleukin‐6 Levels in Gingival Crevicular Fluid and Periodontal Status in Patients With Rheumatoid Arthritis and Adult Periodontitis

Abstract

In the patients with RA, despite increased local tissue destruction potential due to autoimmunity and higher PI levels than in the AP patients, our findings suggest that medication including corticosteroid and non-steroidal anti-inflammatory drugs may decrease gingival inflammation, but the synthesis and degradation of IL-6 in gingival tissue of RA patients may be different. To our knowledge, this study is the first report determining GCF IL-6 levels in RA patients.