Concepedia

Direct access to triazole-olefins through catalytic cycloaddition of azides to unsaturated aldehydes

Wenjun Li, Qianfa Jia, Zhiyun Du, Jian Wang

Chemical Communications · 2013 · 108 citations · 27 references

DOI

Concepts

Abstract

In situ formed dienamines as HOMO-raising dipolarophiles react with azides to afford the corresponding triazole-olefins in good to excellent yields via a catalytic inverse-electron-demand 1,3-dipolar cycloaddition process.

References

27

A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

Vsevolod V. Rostovtsev, Luke G. Green, Valery V. Fokin et al. · Angewandte Chemie International Edition · 2002 · 11.5K citations

, , +8

Peptidotriazoles on Solid Phase:  [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

Christian W. Tornøe, Caspar Christensen, Morten Meldal · The Journal of Organic Chemistry · 2002 · 8.5K citations

, , +12

1,3‐Dipolar Cycloadditions. Past and Future

Rolf Huisgen · Angewandte Chemie International Edition in English · 1963 · 2.8K citations

, , +10

Kinetics and Mechanism of 1,3‐Dipolar Cycloadditions

Rolf Huisgen · Angewandte Chemie International Edition in English · 1963 · 1.2K citations

, , +13

Heterocyclic Peptide Backbone Modifications in an α-Helical Coiled Coil

W. Seth Horne, Maneesh K. Yadav, C.D. Stout et al. · Journal of the American Chemical Society · 2004 · 468 citations · Full text

, , +17