An Innovative LC-MS/MS-Based Method for Determining CYP 17 and CYP 19 Activity in the Adipose Tissue of Pre- and Postmenopausal and Ovariectomized Women Using 13C-Labeled Steroid Substrates - Concepedia

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An Innovative LC-MS/MS-Based Method for Determining CYP 17 and CYP 19 Activity in the Adipose Tissue of Pre- and Postmenopausal and Ovariectomized Women Using 13C-Labeled Steroid Substrates

DOI Full Paper Access

33

Citations

22

References

2014

Year

Toshihiko Kinoshita, Seijiro Honma, Yasuhiro Shibata, Kouwa Yamashita, Yoko Watanabe, Hitoe Maekubo, Mitsunobu Okuyama, Akiko Takashima, Naoki Takeshita

The Journal of Clinical Endocrinology & Metabolism

Abstract

Our findings suggest that adipose tissue acts as an endocrine organ, with CYP17 and CYP19 activity playing an essential role in sex steroid hormone biosynthesis.

References

	Year	Citations

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