Science · 1978 · 144 citations · 21 references
PharmacyMicrobiologyToxicologyEnvironmental ToxicologyMicrobial GeneticsMutagenicity AssessmentChemical Mutagen SafetyChemical Mutagen ScreeningEnvironmental MutagenesisFly Ash-based MaterialsFrameshift MutationsMutagen Sensitivity TestingMutagenic EffectivenessRespirable Particles
Incubation of histidine-requiring auxotrophs of the bacterium Salmonella typhimurium with cyclohexane-, saline-, and serum-soluble surface components of respirable fly ash particles produced an increased number of revertants in two frameshift tester strains. The results are consistent with the hypothesis that both organic and inorganic mutagens are present in coal fly ash.
21