The prevention of nitrosomethylurea-induced mammary tumors by <i>d</i>-limonene and orange oil

Abstract

The monocyclic monoterpenoid d-limonene and its source, orange oil, were found to prevent rat mammary carcinomas induced by the direct-acting carcinogen nitrosomethylurea. This chemopreventive effect was limited to the promotion/progression stage in this carcinogenesis model.