Expression of matrix metalloproteinases, type IV collagen, and interleukin‐10 in rabbits treated with morphine after lamellar keratectomy

Abstract

Topical morphine promoted corneal analgesia for up to 4 days and did not delay corneal re-epithelization. The re-establishment of MMPs and IL-10 to levels close to baseline values at the end of the study and the expression of type IV collagen in both groups reinforce that, with caution, 1% morphine can be used after lamellar keratectomy in rabbits.