HER-2/neu genotype of breast cancer may change in bone metastasis

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

Medicine, Genetics, Oncology +14

Multinational Study of the Efficacy and Safety of Humanized Anti-HER2 Monoclonal Antibody in Women Who Have HER2-Overexpressing Metastatic Breast Cancer That Has Progressed After Chemotherapy for Metastatic Disease

Melody Cobleigh, Charles L. Vogel, Debu Tripathy et al. · Journal of Clinical Oncology · 1999 · 2.8K citations

Medicine, Oncology, Pharmacology +17

Evaluation of HER-2/<i>neu</i> Gene Amplification and Overexpression: Comparison of Frequently Used Assay Methods in a Molecularly Characterized Cohort of Breast Cancer Specimens

Michael F. Press, Dennis J. Slamon, Kerry Flom et al. · Journal of Clinical Oncology · 2002 · 389 citations

Medicine, Cancer Biology, Oncology +16

Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1.

Hitoshi Tsuda, S Hirohashi, Yukío Shimosato et al. · PubMed · 1989 · 317 citations

Medicine, Oncology, Pathology +17

Comparison of HER-2 status between primary breast cancer and corresponding distant metastatic sites

David Gancberg, Angelo Di Leo, Fátima Cardoso et al. · Annals of Oncology · 2002 · 309 citations · Full text

Medicine, Oncology, Pathology +15