Tranilast Prevents the Progression of Chronic Cyclosporine Nephrotoxicity Through Regulation of Transforming Growth Factor β/Smad Pathways

Targeted Disruption of Smad3 Reveals an Essential Role in Transforming Growth Factor β-Mediated Signal Transduction

Michael Datto, Joshua P. Frederick, Li‐Hua Pan et al. · Molecular and Cellular Biology · 1999 · 475 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Smad7 Inhibits Fibrotic Effect of TGF-β on Renal Tubular Epithelial Cells by Blocking Smad2 Activation

Hong‐Jian Zhu, Xiao Ru Huang, Kar Neng Lai et al. · Journal of the American Society of Nephrology · 2002 · 246 citations

Life Sciences, Cell Biology, Pathology +14

Role of transforming growth factor-β1 in experimental chronic cyclosporine nephropathy

Fuad S. Shihab, Takeshi F. Andoh, Amie M. Tanner et al. · Kidney International · 1996 · 214 citations · Full text

Medicine, Nephrology, Pathology +14

Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity

I Guerrero Feria, Israel Pichardo, M. Patricia Juárez et al. · Kidney International · 2003 · 146 citations

Medicine, Nephrology, Pharmacology +11

Therapeutic Role of TGF-β–Neutralizing Antibody in Mouse Cyclosporin A Nephropathy

Hong Ling, Xuemei Li, Sharda Jha et al. · Journal of the American Society of Nephrology · 2003 · 126 citations

Medicine, Nephrology, Pathology +13