ERBB2 Induces an Antiapoptotic Expression Pattern of Bcl-2 Family Members in Node-Negative Breast Cancer - Concepedia

Concepedia

Publication | Closed Access

ERBB2 Induces an Antiapoptotic Expression Pattern of Bcl-2 Family Members in Node-Negative Breast Cancer

59

Citations

42

References

2010

Year

Ilka Petry, Esther Fieber, Marcus Schmidt, Mathias Gehrmann, Susanne Gebhard, Matthias Hermes, Wiebke Schormann, Silvia Selinski, Evgenia Freis, Holger Schwender,

Clinical Cancer Research

Abstract

Our results support the concept that ERBB2 influences the expression of Bcl-2 family members to induce an antiapoptotic phenotype. Antagonization of antiapoptotic Bcl-2 family members might improve breast cancer therapy, whereby MCL-1 and BNIP3 represent promising targets.

References

	Year	Citations

Page 1