Publication | Open Access
Immunotherapy with VGX-3100 (HPV16 and HPV18 plasmids) + INO-9012 (DNA encoding IL-12) in human papillomavirus (HPV) associated head and neck squamous cell carcinoma (HNSCCa): interim safety and immunogenicity results
16
Citations
0
References
2015
Year
ImmunologyPathologyHpv InfectionAbstracts Oropharyngeal HnsccaImmunotherapyTreatment ResistanceCancer-associated VirusHuman Papillomavirus VaccinesHpv18 PlasmidsNeck OncologyInterim SafetyCervical HealthHuman PapillomavirusHpv18 E6/e7VaccinationCervical CancerNeck PathologyHead And Neck CancerHead And Neck Squamous Cell CarcinomaMedicineViral Oncology
Meeting abstracts Oropharyngeal HNSCCa is frequently associated with HPV infection. DNA-based Immunotherapy with plasmids encoding HPV16 and HPV18 E6/E7 antigens has been shown to generate robust immune responses in women with HPV-driven high-grade cervical dysplasia. We hypothesize that HPV-