Korean Circulation Journal · 2015 · 14 citations · 7 references
MedicineCardiologyInternal MedicineCardiovascular PharmacotherapyClinical CardiologyInterventional CardiologyAnticoagulant TherapyAntiplatelet TherapyCoronary AngiographyCoronary Artery DiseaseThrombolytic TherapyThrombosisAnticoagulation During Coronary InterventionAntiplatelet DrugsCoronary Thrombus DetectionCoronary Thrombus ManagementInvasive Coronary AngiographyMultivessel Coronary Artery DiseaseMultivessel Coronary Disease DetectionThrombosis Mechanisms
This case report underscores that crystal methamphetamine abuse is an important cause of multivessel coronary thrombosis and raises doubts about the therapeutic options. The patient was a 34-year-old smoker and crystal methamphetamine abuser with no significant medical history, who presented with retrosternal chest pain associated with cold sweats. Twelve-lead electrocardiogram revealed diffuse ST-segment elevation in I, II, AVL, AVF, and V 2-6 leads. He underwent urgent coronary angiography and it showed Thrombolysis in Myocardial Infarction (TIMI) grade 3 flow in coronary arteries and presence of a thrombus in the left anterior descending artery (LAD) and the right coronary artery (RCA). The patient underwent medical therapy with antiplatelet agents and anticoagulants. Repeat coronary angiography after three months of dual therapy with warfarin and aspirin did not show any thrombus or any significant lesion in the RCA and the LAD having TIMI grade 3 flow.
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Acute Physiological and Behavioral Effects of Intranasal Methamphetamine in Humans
Carl L. Hart, Erik W. Gunderson, Audrey Perez et al. · Neuropsychopharmacology · 2007 · 126 citations · Full text
Acute coronary syndrome and crystal methamphetamine use: a case series.
Mevan Wijetunga, Joseph Lindsay, Steven B. Karch · PubMed · 2004 · 49 citations · Full text
Medicine, Cardiology, Toxicology +16