Concepedia

Temperature shift as a process optimization step for the production of pro-urokinase by a recombinant Chinese hamster ovary cell line in high-density perfusion culture

Zhaolie Chen, Benchuan Wu, Hong Liu, Xingmao Liu, Peitang Huang

Journal of Bioscience and Bioengineering · 2004 · 50 citations · 14 references

DOI

Concepts

References

14

Amplification and expression of sequences cotransfected with a modular dihydrofolate reductase complementary DNA gene

Randal J. Kaufman, Phillip A. Sharp · Journal of Molecular Biology · 1982 · 360 citations

, , +6

Influence of low temperature on productivity, proteome and protein phosphorylation of CHO cells

Hitto Kaufmann, Xenia Mazur, Martin Fussenegger et al. · Biotechnology and Bioengineering · 1999 · 278 citations

, , +17

Factors affecting cell growth and monoclonal antibody production in stirred reactors

Shaul Reuveny, Daniel Uribe-Vélez, James D. Macmillan et al. · Journal of Immunological Methods · 1986 · 267 citations

, , +16

Effect of low culture temperature on specific productivity, transcription level, and heterogeneity of erythropoietin in Chinese hamster ovary cells

Sung Kwan Yoon, Ji Yong Song, Gyun Min Lee · Biotechnology and Bioengineering · 2003 · 244 citations · Full text

, , +15

Effects of temperature shift on cell cycle, apoptosis and nucleotide pools in CHO cell batch cultues

Alison Moore, Jennifer Mercer, George Dutina et al. · Cytotechnology · 1997 · 190 citations

, , +12