Fluorescent Molecular Logic Gates Using Microfluidic Devices

Abstract

Starting gate: A molecular logic gate is based on chemosensors that change their fluorescence intensity in response to various inputs (pH, metal ions) in a microfluidic system. A combinatorial circuit, such as a half adder (see picture), uses fluorescein (green) and rhodamine B (red) derivatives that respond to pH. A logic gate with a protein and Cu2+ ions as inputs is also described. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z703813_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.