High IgE levels to α‐lactalbumin, β‐lactoglobulin and casein predict less successful cow's milk oral immunotherapy

Abstract

Component-resolved diagnostics before OIT can help to identify children with lower probability of a successful OIT outcome, as high IgE levels to α-lactalbumin, β-lactoglobulin and casein are associated with lower maintenance dose reached. An increase in the IgG4 concentration to milk components during treatment indicated effective desensitization.