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Multicenter Phase II Study of Lapatinib in Patients with Brain Metastases from HER2-Positive Breast Cancer

DOIFull Paper Access

656

Citations

17

References

2009

Year

Nancy U. Lin, Véronique Dièras, Devchand Paul, Dominique Lossignol, Christos Christodoulou, Hans‐Joachim Stemmler, Henri Roché, Minetta C. Liu, Richard Greil, Eva Ciruelos,
Clinical Cancer Research

Abstract

This study confirms the modest CNS antitumor activity of lapatinib. Additional responses were observed with the combination of lapatinib and capecitabine. Further studies of lapatinib-based regimens for CNS metastases from HER2+ breast cancer are warranted.

References

YearCitations

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