Concepedia

Publication | Closed Access

MicroRNA 217 Modulates Endothelial Cell Senescence via Silent Information Regulator 1

DOI

478

Citations

26

References

2009

Year

Rossella Menghini, Viviana Casagrande, Marina Cardellini, Eugenio Martelli, Alessandro Terrinoni, Francesca Amati, Mariuca Vasa‐Nicotera, Arnaldo Ippoliti, Giuseppe Novelli, Gerry Melino,
Circulation

Abstract

Our data pinpoint miR-217 as an endogenous inhibitor of SirT1, which promotes endothelial senescence and is potentially amenable to therapeutic manipulation for prevention of endothelial dysfunction in metabolic disorders.

References

YearCitations

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