Lara D. Veeken · 1992 · 12 citations · 0 references
MedicineDermatologyPathologyCellular PathologyDermatopathologySystemic PathologyCutaneous Connective Tissue DisordersCutaneous NeoplasmsMast Cell DisordersMucocutaneous DisordersSkin TumorsSystemic SclerosisCutaneous MucinosisDiffuse Cutaneous Systemic SclerosisDisorderPapular Skin DiseasesSystemic Sclerosis Skin InvolvementUltrastructural CharacterizationUltrastructural CharactersUltrastructural Pathology
Papular mucinosis (scleromyxoedema) is an uncommon disorder characterized by generalized papular eruption and cutaneous induration, which may be associated with a variety of extracutaneous manifestations. Although scleroderma and papular mucinosis share many features, they are clinically and histologically distinct entities. We report here a patient with diffuse scleroderma who developed superimposed papular mucinosis. Degranulating mast cells were a prominent ultrastructural finding in the involved skin. The occurrence of scleroderma and papular mucinosis, two uncommon cutaneous indurative diseases, in the same patient has not been described previously.