A Role for Neural Integrators in Perceptual Decision Making

TLDR

Decision making under uncertainty can be improved by accumulating information over time. The study investigates whether evidence accumulation underlies motion direction decisions in a random‑dot kinematogram. A computational model using MT/V5‑like and LIP‑like neuron ensembles posits that LIP neurons integrate visual evidence until a threshold triggers a decision. The model accounts for diverse behavioral and physiological data from monkeys.

Abstract

Decisions based on uncertain information may benefit from an accumulation of information over time. We asked whether such an accumulation process may underlie decisions about the direction of motion in a random dot kinetogram. To address this question we developed a computational model of the decision process using ensembles of neurons whose spiking activity mimics neurons recorded in the extrastriate visual cortex (area MT or V5) and a sensorimotor association area of the parietal lobe (area LIP). The model instantiates the hypothesis that neurons in sensorimotor association areas compute the time integral of sensory signals from the visual cortex, construed as evidence for or against a proposition, and that the decision is made when the integrated evidence reaches a threshold. The model explains a variety of behavioral and physiological measurements obtained from monkeys.