Concepedia

PAMPA—critical factors for better predictions of absorption

Alex Avdeef, Stefanie Bendels, Lei Di, Bernard Faller, Manfred Kansy, Kiyohiko Sugano, Yukinori Yamauchi

Journal of Pharmaceutical Sciences · 2007 · 241 citations · 45 references

DOI

Concepts

References

45

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

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Physicochemical High Throughput Screening:  Parallel Artificial Membrane Permeation Assay in the Description of Passive Absorption Processes

Manfred Kansy, Frank Senner, Klaus Gubernator · Journal of Medicinal Chemistry · 1998 · 1.3K citations

, , +16

High throughput artificial membrane permeability assay for blood–brain barrier

Li Di, Edward H. Kerns, Kristi Fan et al. · European Journal of Medicinal Chemistry · 2003 · 1.1K citations

, , +11

Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells

Shinji Yamashita, Tomoyuki Furubayashi, Makoto Kataoka et al. · European Journal of Pharmaceutical Sciences · 2000 · 565 citations

, , +14

Predicting plasma protein binding of drugs: a new approach

Nicole A. Kratochwil, Walter Huber, Francis Müller et al. · Biochemical Pharmacology · 2002 · 550 citations

, , +14