Serum Levels of an Isoform of Apolipoprotein A-II as a Potential Marker for Prostate Cancer

Abstract

We have identified an isoform of ApoA-II giving rise to an 8.9K m/z SELDI "peak" that is specifically overexpressed in prostate disease. The ability of ApoA-II to detect disease in patients with normal prostate-specific antigen suggests potential utility of the marker in identifying indolent disease.