<i>TM4SF1</i>, a novel primary androgen receptor target gene over‐expressed in human prostate cancer and involved in cell migration

Abstract

Our results reveal a novel function for TM4SF1 in AR signaling. The TM4SF1 mRNA expression is higher in prostate cancer tissues as compared to BPH samples. Inhibition of cell migration after targeted knockdown of TM4SF1 protein expression suggests its contribution to prostate cancer cell metastasis.