Concepedia

The cellular prion protein mediates neurotoxic signalling of β‐sheet‐rich conformers independent of prion replication

Ulrike K. Resenberger, Anja Harmeier, Andreas C. Woerner, Jessica L. Goodman, Veronika Müller, Rajaraman Krishnan, R. Martin Vabulas, Hans A. Kretzschmar, Susan Lindquist, F. Ulrich Hartl,

The EMBO Journal · 2011 · 242 citations · 45 references

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45

Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Dominic M. Walsh, Igor Klyubin, Julia V. Fadeeva et al. · Nature · 2002 · 4.3K citations

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Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

Rakez Kayed, Elizabeth Head, Jennifer L. Thompson et al. · Science · 2003 · 4.1K citations

, , +17

Diffusible, nonfibrillar ligands derived from Aβ <sub>1–42</sub> are potent central nervous system neurotoxins

Mary P. Lambert, Avlin Barlow, Brett A. Chromy et al. · Proceedings of the National Academy of Sciences · 1998 · 3.5K citations · Full text

, , +17

Mice devoid of PrP are resistant to scrapie

Hansruedi Büeler, Adriano Aguzzi, Andreas W. Sailer et al. · Cell · 1993 · 2.1K citations · Full text

, , +8

Natural oligomers of the amyloid-β protein specifically disrupt cognitive function

James Cleary, Dominic M. Walsh, J. Hofmeister et al. · Nature Neuroscience · 2004 · 1.7K citations

, , +16