Chemiluminescence detection in capillary electrophoresis

Abstract

Abstract Capillary electrophoresis techniques offer high plate numbers and are highly suited for the efficient separation of a wide variety of chemical components in diverse matrices. Because of the small capillary and detection cell dimensions, together with the minute volumes of samples to be injected, sensitive detection devices based on different physicochemical principles are being developed by various scientific groups and companies. The nature, possible applications and limitations of chemiluminescence as a detection technique are outlined in the present manuscript. The technique so far has only been explored by a limited number of research groups, and serious developments are to be expected for the coming years.