Biomedical Papers · 2011 · 69 citations · 13 references
The study confirmed the relationship between age, clinical (CEAP clinical class) and pathophysiological (extent of the venous reflux) severity of CVD Older age means an increased number of insufficient venous segments and increased risk of the clinical progression of CVD from varicose veins to chronic venous insufficiency (C(3)-C(6), trophic skin changes and venous ulcers). Our results support the BMI, in term of frequency of venous reflux, as a risk factor in the whole group of patients but only in women but not in men. Multiple linear regression showed BMI together with age as significant predictors of clinical grade of CVD (p<0.05) according to the CEAP classification. As regards the influence of BMI on clinical severity/grade of CVD (CEAP), the results of our study support BMI as an important risk factor.
13
John J. Bergan, Geert W. Schmid‐Schönbein, Philip Smith et al. · New England Journal of Medicine · 2006 · 905 citations
The Epidemiology of Varicose Veins: The Framingham Study
Frederick N. Brand, Andrew L. Dannenberg, Robert D. Abbott et al. · American Journal of Preventive Medicine · 1988 · 556 citations
Varices, Thrombosis, Venous Disease +10
Patrick Carpentier, Hildegard R. Maricq, Christine Biro et al. · Journal of Vascular Surgery · 2004 · 412 citations · Full text